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Khawla S Al-Kuraya Selected Research

5- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- one

3/2012c-Met inhibitor synergizes with tumor necrosis factor-related apoptosis-induced ligand to induce papillary thyroid carcinoma cell death.
12/2011Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma.
1/2011HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma.

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Khawla S Al-Kuraya Research Topics

Disease

54Neoplasms (Cancer)
07/2021 - 07/2005
19Colorectal Neoplasms (Colorectal Cancer)
11/2021 - 03/2006
10Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
02/2014 - 07/2005
7Papillary Thyroid Cancer
03/2022 - 10/2008
7Ovarian Epithelial Carcinoma
05/2021 - 09/2009
6Neoplasm Metastasis (Metastasis)
12/2021 - 01/2016
6Carcinogenesis
05/2021 - 05/2010
6Lymphoma (Lymphomas)
02/2014 - 07/2005
5Breast Neoplasms (Breast Cancer)
01/2021 - 06/2015
4Ovarian Neoplasms (Ovarian Cancer)
10/2019 - 09/2009
4Primary Effusion Lymphoma
01/2012 - 04/2007
3Lymphatic Metastasis
11/2021 - 01/2021
3Obesity
02/2014 - 09/2009
2Thyroid Neoplasms (Thyroid Cancer)
01/2016 - 01/2011
2B-Cell Lymphoma (Lymphoma, B Cell)
01/2013 - 01/2012
2Carcinoma (Carcinomatosis)
11/2009 - 11/2009
1Endometrial Neoplasms (Endometrial Cancer)
02/2021
1Turcot syndrome
01/2021
1Triple Negative Breast Neoplasms
01/2021
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2011

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
11/2021 - 03/2006
9Phosphotransferases (Kinase)IBA
01/2021 - 01/2010
6Bortezomib (Velcade)FDA Link
01/2018 - 05/2008
5Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
09/2017 - 01/2011
5LeptinIBA
02/2014 - 09/2009
4Biomarkers (Surrogate Marker)IBA
12/2021 - 01/2010
4Protein Kinases (Protein Kinase)IBA
01/2018 - 05/2008
4Leptin ReceptorsIBA
02/2014 - 09/2009
4Fatty Acid Synthases (Fatty Acid Synthase)IBA
01/2011 - 10/2008
3Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2020 - 01/2010
3DNA (Deoxyribonucleic Acid)IBA
01/2019 - 07/2005
3embelinIBA
12/2018 - 07/2015
3Cisplatin (Platino)FDA LinkGeneric
05/2015 - 01/2011
3LigandsIBA
03/2012 - 07/2010
35- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- oneIBA
03/2012 - 01/2011
3TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
12/2011 - 07/2010
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
12/2011 - 09/2010
3EnzymesIBA
01/2011 - 07/2009
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2009 - 12/2006
2IodineIBA
03/2022 - 01/2021
2B7-H1 AntigenIBA
02/2021 - 01/2021
2Factor V (Coagulation Factor V)IBA
01/2021 - 01/2020
2Estrogen ReceptorsIBA
01/2021 - 01/2021
2Progesterone Receptors (Progesterone Receptor)IBA
01/2021 - 01/2021
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2020 - 01/2018
2MethyltransferasesIBA
01/2019 - 07/2005
2Calcibiotic Root Canal SealerIBA
02/2014 - 11/2009
2thymoquinoneIBA
01/2013 - 04/2011
2Thiostrepton (Gargon)IBA
07/2012 - 01/2012
2Proto-Oncogene Proteins c-metIBA
03/2012 - 01/2011
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2012 - 08/2011
2X-Linked Inhibitor of Apoptosis ProteinIBA
01/2012 - 10/2010
2Pharmaceutical PreparationsIBA
07/2011 - 07/2005
2Biological ProductsIBA
07/2011 - 01/2005
2Fatty Acids (Saturated Fatty Acids)IBA
01/2011 - 05/2010
2Proteasome Endopeptidase Complex (Proteasome)IBA
10/2009 - 05/2008
2UbiquitinIBA
10/2009 - 05/2008
2CurcuminIBA
01/2009 - 10/2008
1Cyclin-Dependent Kinase 9IBA
05/2021
1Mi-2 Nucleosome Remodeling and Deacetylase ComplexIBA
01/2021
1Nucleosomes (Nucleosome)IBA
01/2021
1DNA HelicasesIBA
01/2021
1Carrier Proteins (Binding Protein)IBA
01/2021
1tyrosine receptor (receptor, tyrosine)IBA
01/2021
1Indicators and Reagents (Reagents)IBA
01/2021
1Phenobarbital (Luminal)FDA Link
01/2021
1Cyclin D1IBA
01/2021
1Dinoprostone (PGE2)FDA Link
12/2020
1Exonucleases (3' 5' Exonuclease)IBA
01/2020
1Mitogen-Activated Protein KinasesIBA
10/2019
1Drinking WaterIBA
10/2019
1Smad4 ProteinIBA
01/2019
1olaparibIBA
12/2018
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2018
1CateninsIBA
01/2018
1F-Box ProteinsIBA
01/2018
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
09/2017
1ThyroglobulinFDA Link
01/2016
1Anaplastic Lymphoma KinaseIBA
09/2015
1PTEN Phosphohydrolase (PTEN Phosphatase)IBA
06/2015
1Genetic Markers (Genetic Marker)IBA
07/2014
1Mechanistic Target of Rapamycin Complex 2IBA
07/2014
1Mechanistic Target of Rapamycin Complex 1IBA
07/2014
1Tumor Biomarkers (Tumor Markers)IBA
07/2012
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2012
1Transcription Factors (Transcription Factor)IBA
01/2012
1Matrix Metalloproteinases (MMPs)IBA
01/2012
1LipidsIBA
07/2011
1CyclinsIBA
05/2011
1Oxaliplatin (Eloxatin)FDA LinkGeneric
05/2011
1Ubiquitin-Conjugating EnzymesIBA
05/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2011
1Forkhead Box Protein M1IBA
02/2011
1Complementary DNA (cDNA)IBA
02/2011
1CaspasesIBA
01/2011
1ResveratrolIBA
01/2011
1Inhibitor of Apoptosis ProteinsIBA
10/2010

Therapy/Procedure

9Therapeutics
03/2022 - 07/2010
5Drug Therapy (Chemotherapy)
10/2019 - 04/2007
1Lymph Node Excision (Lymph Node Dissection)
01/2021